By Catherine Marcucci, Michael P. Hutchens et al. (eds.)
The prevalence of deleterious or perhaps deadly drug-drug interactions (DDIs) within the perioperative interval is not any longer a theoretical hindrance yet a harrowing truth. A Case method of Perioperative Drug-Drug Interactions addresses the advanced realm of pharmacokinetic drug interactions in an easy-to-read quantity that features as either a entire medical reference and a casebook. The booklet provides a precis of the middle thoughts of drug interactions; an prepared, annotated presentation of the drug interactions such a lot suitable to the perioperative clinician; and nearly 2 hundred case eventualities that spotlight particular drug interactions. This booklet fills a true void within the scientific literature and is worthy to anesthesiologists and surgeons, in addition to trainees in either specialties; extensive care employees, together with physicians, physician’s assistants, and nurses; and nurse practitioners who employees preoperative overview clinics.
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Extra resources for A Case Approach to Perioperative Drug-Drug Interactions
These key pharmacokinetic concepts include the cytochrome P450 (CYP) system, and the roles played by substrates, inhibitors, and inducer in drug interactions. We next present a Brief Review of CYP450 Enzymes and UGTs. This is a compilation and summary of the each of the major enzymes involved in oxidiative (Phase I) metabolism. We have nicknamed each of the enzymes to indicate what their primary business is and to help the reader remember and discriminate between them. A mastery of the P450 enzymes is important as they are prime actors in the occurrence of metabolic DDIs—at least the pharmacokinetic DDIs that involve metabolism.
Anesth Analg. 2008;107:494–506. PharmacokineƟc InteracƟons: Core Concepts 3 Erica D. WiƩwer MD, PhD and Wayne T. Nicholson MD, PharmD, MSc Abstract This chapter discusses the essential terms and concepts pertaining to how the body processes drugs. This subset of pharmacology is known as pharmacokinetics. Introduction to Pharmacokinetics Pharmacokinetics describes what the body does to a drug. This subject is in contrast to pharmacodynamics, which is the relation between the concentration of drug at the effect site and the degree of the resulting drug effect.
John Hache MD and Thomas M. Chalifoux MD 903 204 Determined and Desperate to Diet . . . . . . . . . . . . . . Lisa Chan MD and Kirk Lalwani MD, FRCA, MCR 909 XVIII Drug–Drug Interactions Involving Spices and Supplements 205 Introduction . . . . . . . . . . . . . . . . . . . . . . . Kirk Lalwani MD, FRCA, MCR 915 206 Caffeine Crash . . . . . . . . . . . . . . . . . . . . . . Brian Gierl MD and Ryan Romeo MD 917 207 Sad Sequelae .
A Case Approach to Perioperative Drug-Drug Interactions by Catherine Marcucci, Michael P. Hutchens et al. (eds.)