Acute Kidney Injury - download pdf or read online

By Claudio Ronco, Rinaldo Bellomo, John A., M.D. Kellum

ISBN-10: 3805582714

ISBN-13: 9783805582711

Acute kidney damage is outlined as an abrupt switch in serum creatinine and/or urine output, and a majority of sufferers admitted to the ICU have a few proof of the ailment. regrettably, remedy for this advanced syndrome is as but missing and figuring out is restricted. An interdisciplinary panel of specialists has contributed to this quantity, illuminating a number of the primary and complicated facets of the sickness starting from pathophysiology to remedy, from rising biomarkers to genetic polymorphisms. different contributions concentrate on immunological concerns or the numerous issues of acute kidney harm and co-morbid stipulations encountered, protecting the basics in addition to the most recent advancements. furthermore, vital technical facets of extracorporeal cures together with vascular entry, anticoagulation or fluid composition are brought, and various methods to renal help from intermittent dialysis to non-stop treatments and hybrid strategies are mentioned. an outline of complicated extracorporeal thoughts of organ aid and their function within the administration of sepsis and acute kidney damage within the context of an total technique of multi-organ failure administration concludes the discussions. This quantity not just offers a realistic and up to date precis of present wisdom and expertise, but in addition imparts a basic realizing of the pathogenesis and sure destiny advancements during this box. It additionally serves to problem and reassess the elemental underlying assumptions we carry relating to serious disorder generally and acute kidney harm particularly.

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Crit Care Med 1998;26:1793–1800. Vincent 30 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 Ympa YP, Sakr Y, Reinhart K, et al: Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med 2005;118:827–832. Vinsonneau C, Camus C, Combes A, et al: Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial. Lancet 2006;368:379–385.

JAMA 2005;294:813–818. Feest TG, Round A, Hamad S: Incidence of severe acute renal failure in adults: results of a community based study. BMJ 1993;306:481–483. Waikar SS, Curhan GC, Wald R, McCarthy EP, Chertow GM: Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol 2006;17:1143–1150. Epidemiology of AKI 37 12 13 14 15 16 17 18 19 20 21 22 Goss CH, Brower RG, Hudson LD, Rubenfeld GD: Incidence of acute lung injury in the United States. Crit Care Med 2003;31:1607–1611.

In the context of a more generalized MOF, the increasingly common association of acute renal failure with other organ failures has important implications on patient care, moving management away from the realm of the nephrologists and towards a more multidisciplinary approach. Critical Care Nephrology 27 The Role of the General Intensivist in Critical Care Nephrology Intensivists must be trained and ready to take care of a vast range of acute problems of various etiologies and involving any, or many, organ system(s).

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Acute Kidney Injury by Claudio Ronco, Rinaldo Bellomo, John A., M.D. Kellum


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