Download e-book for kindle: Acute Stroke: Bench to Bedside (Neurological Disease and by Anish Bhardwaj, Nabil J. Alkayed, Jeffrey R. Kirsch, Richard

By Anish Bhardwaj, Nabil J. Alkayed, Jeffrey R. Kirsch, Richard J. Traystman

ISBN-10: 0849398703

ISBN-13: 9780849398704

ISBN-10: 1420021044

ISBN-13: 9781420021042

Because the 3rd prime reason behind demise within the usa, stroke debts for one in each fifteen deaths and is the foremost reason behind incapacity within the nation. Compiled through a well known editorial crew, this reference bridges the space among uncomplicated technological know-how and sufferer care protocols, and collects forty three expertly written chapters that diversity from laboratory-based examine on animal types to the development, mechanisms, therapy, and diagnosis of ailments comparable to subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), focal ischemic stroke, and international cerebral ischemia.

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Extra resources for Acute Stroke: Bench to Bedside (Neurological Disease and Therapy)

Sample text

The effect of nicardipine on vasospasm in rabbit basilar artery after subarachnoid hemorrhage. Neurosurgery 1991; 29:183–188. 70. Vorkapic P, Bevan RD, Bevan JA. Pharmacologic irreversible narrowing in chronic cerebrovasospasm in rabbits is associated with functional damage. Stroke 1990; 21:1478–1484. 71. Frazier JL, Pradilla G, Wang PP, Tamargo RJ. Inhibition of cerebral vasospasm by intracranial delivery of ibuprofen from a controlled-release polymer in a rabbit model of subarachnoid hemorrhage.

With this method, angiographic vasospasm of the basilar artery was reported in 82% of animals 5 days after the first injection (90,91). Further analyses showed histopathologic changes in the basilar artery that were associated with a decreased response to treatment with intra-arterial papaverine. Several experimental studies have been performed with this model. Advantages include a well-defined course of vasospasm that is comparable to that of humans, accessible percutaneous angiography, and histopathologic and pharmacologic changes.

Effect of intrathecal superoxide dismutase and catalase on oxyhemoglobin-induced vasospasm in monkeys. Neurosurgery 1992; 30:529–539. 49. Macdonald RL, Weir BK, Young JD, Grace MG. Cytoskeletal and extracellular matrix proteins in cerebral arteries following subarachnoid hemorrhage in monkeys. J Neurosurg 1992; 76:81–90. 50. Handa Y, Kabuto M, Kobayashi H, Kawano H, Takeuchi H, Hayashi M. The correlation between immunological reaction in the arterial wall and the time course of the development of cerebral vasospasm in a primate model.

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Acute Stroke: Bench to Bedside (Neurological Disease and Therapy) by Anish Bhardwaj, Nabil J. Alkayed, Jeffrey R. Kirsch, Richard J. Traystman


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