J.H.U. Brown, James Francis Dickson's Advances in Biomedical Engineering. Volume 2 PDF

By J.H.U. Brown, James Francis Dickson

ISBN-10: 0120049023

ISBN-13: 9780120049028

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Extra resources for Advances in Biomedical Engineering. Volume 2

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R a l p h et al. found t h a t a r h y t h m of pineal melatonin persists after blinding or in darkness, although persistent light leads to persistent suppression of melatonin. N i r and associates (1971) found t h a t pinealectomy led to a persistent increase in plasma corticosterone in rats. T h e y also found evidence t h a t light can stimulate the pituitary in the absence of the pineal, and t h a t the two possible effects of light (direct stimulation and suppression of melatonin) do not exhibit summation.

Circadian Rhythm. , 1956; Halberg et al, 1959). An increase in secretion of Cortisol in m a n , or of corticosterone in the rat, usually accompanies awakening. Migeon and associates (1956) found t h a t the r h y t h m in corticosteroids was related to the cycle of activity, and t h a t it persisted in blind subjects. T h e y suggested t h a t the r h y t h m of Cortisol was coupled to the sleep-wake cycle. However, Orth and Island (1969) found t h a t the r h y t h m of corticosteroids did not synchronize with the sleep-wake cycle in a blind subject.

GANN A N D GEORGE L. CRYER herein is inherently quite noisy, and the precision of regulation we recognize as homeostasis derives not from the precision of any one subsystem b u t rather from the coordination among subsystems. Clearly, some large questions remain concerning the control of adrenocortical secretion and concerning the significance of this control. D. Models 1. Dynamics of the of the Controller Controller I n the sense of providing a complete integration of the kinds of evidence summarized above, it can be said categorically t h a t there is not available now nor has there been a comprehensive model of the controller of the adrenocortical control system.

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Advances in Biomedical Engineering. Volume 2 by J.H.U. Brown, James Francis Dickson

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