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By Gaston R. Vantrappen M.D., Agg. H.O., Jan J. Hellemans M.D., Agg. H.O. (auth.)

ISBN-10: 3642864295

ISBN-13: 9783642864292

ISBN-10: 3642864317

ISBN-13: 9783642864315

This booklet goals to be a synthesis of our present wisdom in regards to the general and pathological esophagus. even though a few first-class monographs on restricted elements of esophageal pathology can be found, a contemporary instruction manual treating the entire of esophageal body structure and pathology is missing. We tried to offer the amassed fabric in this sort of manner that even the neophyte within the box wouldn't wander off within the wealth of knowledge. consequently we now have incorporated a couple of illustrations reminiscent of classical radiological and endoscopic photos, manometric tracings and easy graphs, that could look superfluous for experts yet should be priceless to the reader who desires to be initiated within the topic. even as we attempted to be quite whole with a purpose to make on hand to the esophageal professional a e-book of references, to which he can with no trouble flip whilst confronted with infrequent illnesses or strange physiological or pathophysiological pheno­ mena. so one can in achieving either goals the authors usually provide their very own standpoint whilst confronted with controversal subject matters, whereas classical in addition to newer beneficial properties and ideas are pointed out and diverging evaluations discussed.

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Mag. X 8300 Electron Microscopy 23 spersed between loosely woven bundles of tonofilaments (F) (Fig. 8 1, 2). These tonofilaments (circa 60 A in diameter) are a characteristic structure in basal cells and run mainly in their long axis, making contact with the attachment plaques of the desmosomes. Tonofilaments are almost absent from an area at the inferior pole of the nucleus where mitochondria are more abundant. Lipid inclusions (L) are occasionally seen near the inferior pole of the nucleus of some basal cells (Fig.

In animals which consume fibrous food, like ruminants or rodents, the esophageal epithelium undergoes complete cornification, similar to the mammalian epidermis, with a well developed granular and horny layer. 7B). The latter are arranged in linear rows running parallel with the longitudinal axis of the esophagus and resembling in their general arrangement those found in the skin of the palmar surfaces (GOETSCH, 1910). Besides conical papillae, elongated ridges of the lamina propria also occur; they run in a direction parallel with the long axis of the esophagus and are connected with one another by ohlique ridges (GOETSCH, 1910).

9 9 ). Keratohyaline granules are virtually absent from these cells. Towards the surface the nuclei appear shrunken and more or less deeply indented. Occasionally desintegration of the nucleus (N) occurs, leaving only remnants of the nuclear envelope (Fig. 9 10}. The topmost cell, facing the lumen (L) appears markedly flattened (Fig. 9 11 ). Cells from this superficial layer seem to separate from the underlying cells by rupture of the desmosomes (Fig. 9 10 , 11). This absence of desmosomal structures is in striking contrast with their abundance in the deeper layers of the stratum spinosum.

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Diseases of the Esophagus by Gaston R. Vantrappen M.D., Agg. H.O., Jan J. Hellemans M.D., Agg. H.O. (auth.)


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